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t
- T cell
Type of lymphocyte (immune cell) that plays an important role in immune responses and targeted cell killing, also known as a T lymphocyte.
- T lymphocyte
Type of lymphocyte (immune cell) that plays an important role in immune responses and targeted cell killing, also known as a T lymphocyte.
- Tandem transplant
Type of transplantation technique where a patient receives two planned transplants within a short period of time. Patients may receive 2 autologous transplants or an autologous stem cell transplant followed by a mini-transplant two to four months afterward.
- Teratogenic
Relating to or causing birth defects.
- Thalomid (thalidomide)
Older oral drug with multiple anti-myeloma effects. Thalomid has been shown to be effective in newly diagnosed and relapsed or refractory myeloma alone and in combination with agents such as dexamethasone. It is chemically similar to Revlimid®.
- Thrombocytopenia
Decrease in the number of platelets (small cell fragments in the blood that help it to clot). A low level of platelets may increase the chance of bleeding.
- Time to progression (TTP)
A measure of time after a disease is treated until the disease starts to get worse or progress.
- Tissue-type plasminogen activator (t-PA)
Enzyme that helps dissolve blood clots and inhibits angiogenesis.
- Toxic epidermal necrosis (TEN)
A rare but life-threatening skin reaction, where skin turns very red and peels off, similar to what you would see with a severe burn. It typically occurs as a side effect to certain drugs but may also appear as a result of infection or suppression of the immune system.
- Translocation
An abnormal change in the DNA where two segments of different chromosomes switch positions.
- Treatment cycles
The period in which treatment is given (e.g., 21 days or 28 days). It is usually followed by a rest period in between treatments.
- Tumor-induced hypercalcemia (TIH)
Condition occurring in various forms of cancer noted by elevated levels of calcium in the blood due to increased bone destruction; also known as hypercalcemia of malignancy (HCM).
- Tumor lysis syndrome
A condition that can occur during cancer treatment when large numbers of cancer cells die; the breaking up of the cells and release of the material into the blood can cause organ damage.
- Tumor microenvironment
The normal cells, molecules and blood vessels that surround and feed a tumor cell. A tumor can change its microenvironment, and the microenvironment can affect how a tumor grows and spreads.
- Tumor necrosis factor-alpha (TNF-a)
Cytokine with several effects in myeloma, including promotion of the growth of myeloma cells and activation of osteoclasts.
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