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- Grade 1 Adverse Event (AE)
A mild side effect resulting from a medical therapy. Minimal or no symptoms may be present and typically medical intervention is not required.
- Grade 2 AE
A moderate side effect resulting from a medical therapy. Depending on the nature of the side effect, medical intervention may or may not be needed.
- Grade 3 AE
A severe side effect resulting from a medical therapy. This side effect typically interferes with patient functioning and requires medical intervention.
- Grade 4 AE
A life-threatening or disabling side effect resulting from a medical therapy. Immediate medical intervention is required.
- Graft-versus-host disease (GVHD)
Complication of allogeneic transplants resulting from donor immune cells recognizing the recipient’s cells as foreign and mounting an attack against them.
- Graft-versus-myeloma effect
Beneficial effect of allogeneic transplants resulting from the donor cells mounting an attack on the recipient’s myeloma cells.
- Granulocyte
Type of white blood cell important in fighting infection. Neutrophils are the most abundant type of granulocyte.
- Granulocyte colony-stimulating factor (G-CSF)
A drug that stimulates the production of infection-fighting white blood cells known as granulocytes. G-CSF is used to help prevent low white blood cell counts and infection in patients receiving chemotherapy and/or stem cell transplants and is also used to help mobilize stem cells prior to(...) - Granulocyte-macrophage colony-stimulating factor (GM-CSF)
A drug that may be used as an alternate to G-CSF (see above). It stimulates the production of infection-fighting white blood cells known as granulocytes and macrophages. Similar to G-CSF, GM-CSF is used to help prevent low white blood cell counts and infection in patients receiving(...) - Growth factors
Drugs that are used to stimulate the production of certain types of cells. The most commonly used growth factors are red blood cell growth factors (also known as erythropoietin) and white blood cell growth factors (also known as colony stimulating factors or CSFs).
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