Glossary

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ALL 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Results: 14

n
Natural killer (NK) cell
Type of white blood cell important in killing tumor cells.
Near complete response (near CR)
Response to therapy where M protein is no longer detectable in the blood and/or urine using conventional tests, but is detectable with the more sensitive immunofixation test, and there are less than 5% plasma cells in the bone marrow.
Nephrotoxicity
Toxicity to the kidneys.
Neuropathic Pain
Chronic pain caused by damage to, or dysfunction of, nerves.
Neuropathy
Disorder of the nerves that can result in abnormal or decreased sensation or burning/tingling. When the hands and feet are affected, it is referred to as peripheral neuropathy.
Neutropenia
Below-normal number of neutrophils.
Neutrophil
Type of white blood cell that plays an important role in the immune system (e.g., can destroy bacteria).
New Drug Application (NDA)
Compilation of information on the safety and efficacy of a new drug that is submitted to the U.S. Food and Drug Administration (FDA) in order to request approval to market the drug as therapy for a disease indication.
Newly diagnosed disease
Multiple myeloma that has not yet been treated.
Non-myeloablative allogenic transplant
See mini-allogeneic transplant
Nonsecretory myeloma
Rare form of myeloma affecting about 1% of myeloma patients where the malignant plasma cells do not secrete M protein or light chains.
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Common types of painkillers. There are both over-the-counter NSAIDs as well as prescription NSAIDs. Examples of over-the-counter NSAIDs include aspirin, Motrin® (ibuprofen) and Aleve® (naproxen)
Novel erythrocyte stimulating protein (NESP)
Protein that stimulates the bone marrow to produce red blood cells.
Nuclear factor ?B (NF-?B)
Key survival protein found within the cell that acts as a messenger. When a cell receives an external signal, such as a growth factor, NF-kB transfers the message to the nucleus of the cell, causing some type of response, such as cell growth.