When Amy McKnett’s mother, Deb, was diagnosed with multiple myeloma, it came as a shock to Amy and her family. Despite Deb’s faith, strength and determination, the disease progressed quickly, and sadly, Deb’s battle with this disease was hard-fought but short. After Deb’s passing in October of 2022, Amy and her family learned of the Multiple Myeloma Research Foundation® (MMRF®) and felt compelled to do something meaningful in her honor.
“Watching her face such a relentless illness with grace and courage changed our lives forever,” Amy shared. The MMRF’s commitment to innovation and patient support resonated with Amy and her family, and they quickly knew they had found a way to channel their grief into purpose.
To celebrate Deb’s life and spirit, Amy decided to create a team for the MMRF Walk/Run Philadelphia, naming her team Nana’s Legacy, to honor her mother’s memory and stand alongside others who have been affected by multiple myeloma. “Every step we take with Nana’s Legacy is a reminder that her spirit lives on — and that together, we’re making a difference.” Amy and her team walk in tribute to the strength, love and resilience that Deb showed not only during her battle with multiple myeloma, but also in life.
Amy is incredibly honored to be recognized as Philadelphia’s Spirit of Hope Honoree this year. For Amy, it’s not just an honor — it’s a reflection of the love, strength and generosity that her mother embodied throughout her life and during her battle with multiple myeloma. “To have our team recognized as the Spirit of Hope is a tribute to her spirit and the legacy she left behind.”
This honor reminds Amy and her family that hope is something we carry forward — not just for ourselves, but for every patient, every family, and every future breakthrough. “It affirms that our efforts matter, and that through love, community, and commitment, we can help bring real change. We accept this honor in her name, and with hearts full of gratitude.”
Through her support of MMRF and by participating in the MMRF Walk/Run Philadelphia event, Amy carries on her mother’s legacy. Her mother persevered through her unwavering faith, boundless love and quiet strength. Her devotion as a caring mother, grandmother, and friend throughout her fight allowed her to keep going during her battle. Deb never let the disease define her — her family gave her purpose, and through getting involved with the MMRF, Amy and Nana’s Legacy hold Deb’s teachings, perseverance, and memory closely.